Theko e Khethehileng bakeng sa 2, 5-Dimethoxybenzaldehyde CAS 93-02-7 Intermediate
Ka tloaelo re nahana le ho itloaetsa ho lumellana le phetoho ea maemo, 'me re hole. Re ikemiselitse ho fihlela katleho ea kelello le 'mele e ruileng le ho phela ka Theko e Khethehileng bakeng sa 2, 5-Dimethoxybenzaldehyde CAS 93-02-7 Intermediate, Mopresidente oa k'hamphani ea rona, ka basebeletsi bohle, o amohela bareki bohle ba tlang ho ea koporasi ea rona le ho hlahloba. Ha re sebelisane ka matsoho ho theha nako e telele e monate.
Ka tloaelo re nahana le ho itloaetsa ho lumellana le phetoho ea maemo, 'me re hole. Re ikemiselitse ho fihlela katleho ea kelello le 'mele e ruileng le ba phelang bakeng sa93-02-7 le 2 5-Dimethoxybenzaldehyde, Ke mehlala e tšoarellang mme e khothaletsoa lefatšeng ka bophara. Ha ho na maemo a nyamelang mesebetsi ea bohlokoa ka nako e khuts'oane, ke ntho e lokelang ho etsoa molemong oa hau ka boleng bo botle. E tataisoa ke molao-motheo oa Prudence, Efficiency, Union and Innovation. khoebo e etsa boiteko bo matla ba ho holisa khoebo ea eona ea machabeng, ho phahamisa khoebo ea eona. rofit le ho ntlafatsa sekala sa eona sa thomello. Re na le ts'epo ea hore re tla ba le tebello e matla le e tla ajoa lefatšeng ka bophara lilemong tse tlang.
2,5-Dimethoxybenzaldehyde ke phofo e khanyang ea kristale e mosehla e boima ba molek'hule ea 166.18 le ntlha e belang ea 146 ° C. E qhibiliha ka har'a metsoako ea tlhaho e kang ethanol le ether. E sebelisoa haholo-holo e le setsi sa meriana.
| ITEM | TS'ELISO |
| Ponahalo | Boputsoa ho isa ho bosehla bo tiileng |
| NMR | Latela |
| Bohloeki | >98% |
| Sebaka se qhibilihang | 46-48 °C (hote.) |
| Likahare tsa metsi | <0.5% |
Ntle le ho ba oxidized kapa ho fokotsoa ho 2,5-dimethoxybenzoic acid, benzonitrile kapa benzyl joala, 2,5-dimethoxybenzaldehyde ka boeona le eona e na le boleng bo ikhethang ba ts'ebeliso. Ka ho sebetsana le lintho tse nang le mefuta e fapaneng ea lihlopha tse sebetsang, limolek'hule tsa lithethefatsi tse nang le mekhoa e fapaneng le liphello tse fapaneng li ka fumanoa. Boloetse ba Parkinson (PD) ke lefu le tloaelehileng la neurodegenerative, 'me matšoao a lona a mantlha a kenyelletsa ho thothomela ha mesifa, ho satalla, mathata a ho sisinyeha, boemo ba 'mele le mathata a ho leka-lekanya ho sisinyeha. Ntlafatso e eketsehileng e tla boela e lebise tlhokomelo, temoho, mathata a ho hopola le 'dementia' e totobetseng. Hajoale, kalafo ea PD e kenyelletsa haholo kalafo ea lithethefatsi, kalafo ea opereishene le kalafo ea lefutso. Ka phekolo ea lithethefatsi, phenamidine e fumanoe e e-na le phello e ntle ho PD, e nang le chefo e tlaase le polokeho e ntle, 'me motsoako oa phenamidine o hloka tšebeliso ea 2,5-dimethoxybenzaldehyde e le ntho e qalang.
Ho ea ka mokhoa oa ho kopanya o tlalehiloeng libukeng, 2,5-dimethoxybenzaldehyde e fumanoa haholo-holo ka ho arabela 1,4-dimethoxybenzene ka moemeli oa formylation. Lisebelisoa tsa formylation li kenyelletsa (1) motsoako oa 1,1-dichloromethyl ether le titanium tetrachloride; (2) motsoako oa N, N-dimethylformamide le phosphorus oxychloride, motsoako oa N, N-dimethylformamide le oxalyl chloride; (3) motsoako oa N, N-dimethylformamide le thionyl chloride kapa motsoako oa urotropine le magnesium chloride. Leha ho le joalo, mekhoa ena e hloka tšebeliso ea tekanyo e ngata ea titanium tetrachloride, phosphorus oxychloride kapa thionyl chloride. Li-reagents tsena ha li tsitse ebile li senyeha habonolo, 'me palo e kholo ea khase ea hydrochloric acid e lokolloa nakong ea karabelo, e seng botsoalle ba tikoloho ebile e na le litlhoko tse phahameng bakeng sa ts'ebetso ea ts'ebetso.
Ho hlahisitsoe mokhoa o mocha oa ho kopanya. Mokhoa ona o sebelisa 1,4-dimethoxybenzene le formaldehyde e le lisebelisoa tse tala, 'me o etsa photooxidative coupling reaction ka pel'a oksijene le catalyst tlas'a mahlaseli a khanyang a maputsoa ho kopanya hantle 2,5-dimethoxybenzaldehyde. Mokhoa ona o sebelisa oksijene kapa moea e le oxidant, ha o hlahise khase e nang le asiti, hape o baballa tikoloho. Ho phaella moo, mokhoa ona o sebelisa cobalt e theko e tlaase e le mokelikeli, o theko e tlaase ebile o loketse ts'ebeliso ea indasteri.
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Ka tloaelo re nahana le ho itloaetsa ho lumellana le phetoho ea maemo, 'me re hole. Re ikemiselitse ho fihlela katleho ea kelello le 'mele e ruileng le ho phela ka Theko e Khethehileng bakeng sa 2, 5-Dimethoxybenzaldehyde CAS 93-02-7 Intermediate, Mopresidente oa k'hamphani ea rona, ka basebeletsi bohle, o amohela bareki bohle ba tlang ho ea koporasi ea rona le ho hlahloba. Ha re sebelisane ka matsoho ho theha nako e telele e monate.
Theko e khethehileng bakeng sa93-02-7 le 2 5-Dimethoxybenzaldehyde, Ke mehlala e tšoarellang mme e khothaletsoa lefatšeng ka bophara. Ha ho na maemo a nyamelang mesebetsi ea bohlokoa ka nako e khuts'oane, ke ntho e lokelang ho etsoa molemong oa hau ka boleng bo botle. E tataisoa ke molao-motheo oa Prudence, Efficiency, Union and Innovation. khoebo e etsa boiteko bo matla ba ho holisa khoebo ea eona ea machabeng, ho phahamisa khoebo ea eona. rofit le ho ntlafatsa sekala sa eona sa thomello. Re na le ts'epo ea hore re tla ba le tebello e matla le e tla ajoa lefatšeng ka bophara lilemong tse tlang.
